Resveratrol

Resveratrol bụ antitoxin polyphenolic dị n'ụdị osisi dị iche iche, gụnyere ahụekere, tomato na mkpụrụ vaịn, nke a na-ahụkarị na mgbọrọgwụ polygonum cuspidatum.A na-eji Resveratrol agwọ ọnya na Asia ruo ọtụtụ narị afọ.N'afọ ndị na-adịbeghị anya, a na-ekwu na uru ahụike nke mmanya na-acha uhie uhie bụ ọnụnọ ya na mkpụrụ vaịn.Mkpali a sitere na emume a maara dị ka French Paradox.

Otu dọkịta Irish aha ya bụ Samuel Blair tụpụtara ya mbụ Paradox French na akwụkwọ agụmakwụkwọ e bipụtara na 1819. Ndị France hụrụ nri n'anya, na-eri nri nwere calorie na kọlesterol dị elu, mana ha nwere ọrịa obi dị ala karịa ka ha na-asụ Bekee. ogbo.Yabụ kedu ihe kpatara nke a ji eme?Dị ka nnyocha e mere si kwuo, ndị obodo na-ejikarị mmanya tannin na-eri nri iji soro nri ahụ.Mmanya na-acha uhie uhie nwere resveratrol, nke na-egbochi mkpụkọ ọbara, na-ebelata mbufụt, na-akwalite mgbasa nke arịa ọbara ma na-egbochi nje bacteria.

Achọpụtara Resveratrol na 1924 maka oge mbụ na nyocha nke ndu.Ndị Japan chọtara resveratrol na mgbọrọgwụ osisi na 1940. N'afọ 1976, ndị Britain hụkwara resveratrol na mmanya, ọ nwere ike iru 5-10mg / kg na nnukwu mmanya uhie uhie.Enwere ike ịchọta resveratrol na mmanya, n'ihi na akpụkpọ mkpụrụ vaịn a na-eji eme mmanya nwere resveratrol.Na usoro nke ime mmanya na omenala handwork usoro, resveratrol na-abanye n'ime usoro mmepụta mmanya na skins mkpụrụ vaịn, n'ikpeazụ agbaze nwayọọ nwayọọ tinyere ntọhapụ nke mmanya na mmanya.Na 1980s, ndị mmadụ ji nwayọọ nwayọọ chọpụta ịdị adị nke resveratrol na osisi ndị ọzọ, dị ka mkpụrụ cassia, polygonum cuspidatum, ahụekere, mulberry na osisi ndị ọzọ.

Ọmụmụ ihe gbasara ihe ọkụkụ egosila na resveratrol eke bụ ụdị antitoxin nke osisi na-ezobe n'ihu ahụhụ ma ọ bụ mwakpo nje.Njikọ nke resveratrol na-abawanye nke ọma mgbe ekpughere ya na radieshon ultraviolet, mmebi n'ibu na ọrịa fungal, ya mere a na-akpọ ya ọgwụ nje.Resveratrol nwere ike inyere osisi aka ịlụ ọgụ megide nrụgide mpụga dị ka trauma, nje bacteria, ọrịa na radieshon ultraviolet, n'ihi ya, ọ bụghị nke ukwuu ịkpọ ya onye nlekọta anụ ahụ.

Resveratrol ka egosipụtara na ọ nwere antioxidant, radical free, mgbochi tumor, nchebe obi na mmetụta ndị ọzọ.
1.Antioxidant, mmetụta radical na-enweghị ihe mgbochi- Resveratrol bụ antioxidant eke, ọrụ kachasị mkpa bụ iwepụ ma ọ bụ gbochie ọgbọ nke free radicals, na-egbochi peroxidation lipid, na ịhazi ọrụ nke enzymes metụtara antioxidant.
2.Anti-tumor mmetụta- Mmetụta mgbochi tumor nke resveratrol gosiri na ọ nwere ike igbochi mmalite, nkwalite na mmepe nke tumor.Ọ nwere ike imegide ọrịa kansa afọ, ọrịa ara ara, ọrịa imeju, leukemia na mkpụrụ ndụ etuto ndị ọzọ ruo ogo dị iche iche site na usoro dị iche iche.
3.Cardiovascular nchedo- Resveratrol na-achịkwa ọkwa cholesterol ọbara ma na-ebelata ihe ize ndụ nke ọrịa obi site na ijikọta ndị na-anabata estrogen n'ime ahụ.Ọzọkwa, resveratrol nwekwara mmetụta anti-platelet agglutination, nke nwere ike igbochi platelet ịgbakọta na-etolite mkpụkọ ọbara na-arapara n'ahụ mgbidi arịa, si otú na-egbochi na ibelata omume na mmepe nke ọrịa obi.
4.Estrogen mmetụta- Resveratrol yiri usoro na estrogen diethylstilbestrol, nke na-ejikọta na estrogen anabata ma na-arụ ọrụ nke estrogen mgbaàmà transduction.
5.Anti-inflammatory na antimicrobial mmetụta- Resveratrol nwere mmetụta inhibitory na Staphylococcus aureus, catacoccus, Escherichia coli na Pseudomonas aeruginosa.Nnyocha nyocha nke mgbochi mkpali egosiwo na resveratrol nwere ike nweta mmetụta ọgwụgwọ site n'ibelata nchikota platelet na ịgbanwe ọrụ platelet n'oge usoro mgbochi mkpali.

Ụlọ ọrụ anyị na-etinye aka na mmịpụta resveratrol maka ihe karịrị afọ 20, nwere ọtụtụ mmepụta ihe, nchọpụta na ahụmahụ mmepe.Mmetụta nri dị mma nke Resveratrol bụ nke ndị mmadụ dị iche iche na-echekarị.Dabere na amụma ahịa, ikike nke resveratrol ga-eji dị ka ihe mgbakwunye siri ike, karịsịa maka ọrịa ụfọdụ.Ihe mgbakwunye nri bụ otu n'ime mpaghara resveratrol a na-ejikarị eme ihe, ụlọ ọrụ ihe ọṅụṅụ na-anabatakwa karịa ụlọ ọrụ nri maka nri na ihe ọṅụṅụ ọhụrụ, karịsịa ihe ọṅụṅụ ike.Na mgbakwunye, mmasị nke ndị na-azụ ahịa maka ngwaahịa sitere n'okike ga-akpalikwa ojiji resveratrol zuru ebe niile na mgbakwunye.

Dị ka ọnụ ọgụgụ na-ezughị ezu, oriri zuru ụwa ọnụ nke resveratrol mụbara site na nkezi uto nke 5.59%.Kemgbe afọ 2015, United States agụtala pasentị 76.3 nke ngwaahịa resveratrol ọhụrụ nke ụwa, ebe Europe nwere naanị pasentị 15.1.Ugbu a, imirikiti ngwaahịa nri resveratrol sitere na United States.Achọ maka resveratrol na-abawanye n'ihi nnukwu ọchịchọ maka ngwaahịa ala.

N'ikwekọ n'echiche nke ịbụ onye na-ahụ maka ọha na eze, ụlọ ọrụ na ndị ọrụ, Uniwell biotechnology na-etinyekarị ihe dị mkpa na njikwa nke usoro mmepụta na nyocha nke ngwaahịa.Site raw material procurement, mmepụta, nkwakọ, ahịa na mgbe-sales ọrụ, anyị na-ukwuu agbaso ụkpụrụ GMP chọrọ maka management.We nwere a siri ike àgwà mmesi obi ike otu, elu nnyocha akụrụngwa (HPLC, GC, wdg) na akụrụngwa, na guzosie ike a usoro njikwa mma siri ike.

Anyị na-akwado ịrụ ọrụ nke ọma ụlọ ọrụ, kpebisiri ike na-ewu ihe oru oma osisi wepụ mmepụta enterprise, na-enye eke, elu-edu osisi wepụ ngwaahịa maka nri, ike ngwaahịa, ntecha, ọgwụ na ndị ọzọ na ọrụ.