Andrographolide

Andrographolide bụ ngwaahịa ihe ọkụkụ nke ewepụtara site na ahịhịa nke na-eme na China. Umu ahihia a nwere otutu ihe eji eme ihe na TCM maka ogwugwu oria iku ume iku ume na oria ndi ozo na oria. E webatara Andrographis paniculata ma zụlite na Guangdong na mpaghara ndịda Fujian na 50s. A na-eji ya agwọ ụdị ọrịa dị iche iche na agwọ agwọ. N'afọ ndị na-adịbeghị anya, a na-amụ ihe na China, ihe ọmụmụ, ọgwụ mejupụtara, nkà mmụta ọgwụ na akụkụ ahụike nke Andrographis paniculata. Andrographis paniculata bụ ọgwụ ndị China a na-ejikarị eme ihe, nke nwere mmetụta nke ikpochapu okpomọkụ na toxin, ịjụ ọbara na iwepụ. Clinically, ọ na-bụ-eji maka ọgwụgwọ nke akụkụ okuku ume na tract ọrịa, nnukwu bacillary ọnyụnyụ ọbara, gastroenteritis, oyi, ọkụ na ọbara mgbali. Site na mmụba nke ọgwụ nje na mmeghachi omume na-adịghị mma, olu nke ịmepụta ọgwụ ọdịnala ndị China nwere ezigbo mmetụta antibacterial na-eto. Andrographis paniculata, dị ka ọgwụ ọdịnala ndị China nwere mmetụta antibacterial, ka ụlọ ọrụ ọgwụ na-akwụkwu ụgwọ

A na-amata Andrographis paniculata wepụ osisi nwere ọtụtụ ọrụ ọgwụ. Andrographolide, isi ihe mejupụtara nke wepụ nwere ihe metụtara ọrụ ọgwụ ya. Anyị na-amụ usoro selula na ebumnuche nke ọgwụgwọ andrographolide na-agbanwe n'ọrịa cancer mmadụ na sel ndị na-enweghị nsogbu. Ọgwụgwọ Andrographolide gbochiri in vitro ịba ụba nke usoro mkpụrụ ndụ tumo dị iche iche, na-anọchite ụdị ọrịa kansa dị iche iche. Thelọ ọrụ ahụ na-arụ ọrụ anticancer na mkpụrụ ndụ kansa site na njide mkpụrụ ndụ na mkpụrụ ndụ G0 / G1 site na ntinye nke protein p-cell inhibit p27 ma belata okwu nke 4 kinase na-adabere na cyclin (CDK4). Ihe na-egbochi ọrịa ọgwụ na andrographolide bụ nke a na-egosipụta site na mmụba ụba nke lymphocytes na mmepụta nke interleukin-2. Andrographolide mekwara ka etuto ahụ necrosis factor-alpha Production na CD akara ngosi, na-ebutewanye ọrụ cytotoxic nke lymphocytes megide mkpụrụ ndụ kansa, nke nwere ike inye aka maka ọrụ anticancer na-enweghị isi. A na-egosiputa ihe omume vivo anticancer nke onyinye a megide B16F0 melanoma syngenic na HT-29 xenograft. Nsonaazụ ndị a na-egosi na andrographolide bụ ọgwụ na-atọ ụtọ nke nwere ọgwụ mgbochi na ihe ndị na-eme ka ọ ghara ịmalite ịmalite ịmalite ịmalite ịmalite ịmalite ịmalite ịrịa ọrịa kansa.


Post oge: Jun-22-2021